Side effect What is it? What should I do if it happens to me?
COMMON
AKATHISIA
You feel restless, unable to feel comfortable
unless you are moving.
Tell your doctor about this. It may be possible to change your drug or dose, or
give you something to reduce these feelings.
MOVEMENT
DISORDERS
Feeling shaky or having a tremor. Your neck
may twist back. Your eyes and tongue may
move on their own.
It is not usually dangerous. If it is bad or worries you, tell your doctor. He or
she can give you something for it.
RAISED
PROLACTIN
Prolactin is a natural chemical we all have.
High levels can affect periods in women or
cause impotence in men. It may also cause
breast tenderness and milk secretion, in men
as well as women.
This sometimes wears off in a few weeks, but discuss this with your doctor
anyway. It may be that a change in dose or different drug will help.
WEIGHT GAIN
Eating more and putting on weight. Avoid fatty foods like chocolate, crisps and fizzy drinks. A diet full of
vegetables and fibre will usually help, as will physical activities such as
walking. If it becomes a problem or you are worried, ask to see a dietician.
LESS COMMON
DROWSINESS
Feeling sleepy or sluggish. Don’t drive or use machinery. As your treatment continues you should feel
less drowsy.
UNCOMMON
Dry mouth. Not much saliva or spit. Sugar-free boiled sweets, chewing gum or eating citrus fruits usually helps. If
not, your doctor can give you a mouth spray. A change in medicine or dose
may be possible.
Blurred vision Things look fuzzy and you can’t focus properly. See your doctor if you are
worried. You won’t need glasses.
Feeling "bunged up" inside. You can't pass a
motion or stool.
Eat more fibre e.g. bran, fruit and vegetables. Do more walking. Make sure
you drink plenty of fluid. A mild laxative from a pharmacy might help.
ANTI-
CHOLINERGIC
EFFECTS
Difficulty in passing urine Contact your doctor now.
SEXUAL
DYSFUNCTION
Finding it hard to have an orgasm. No desire
for sex. Men can become impotent.
Discuss this with your doctor when you next meet.
SWELLING
AND NODULES
Injection site swells. It feels painful and lumpy. Report it to your nurse. Warm baths and regular exercise like walking can
help.
RARE
HYPOTENSION
A low blood pressure. You may feel faint when
you stand up.
Try not to stand up too quickly. If you feel dizzy, don’t drive. This dizziness is
not dangerous
VERY RARE
URINE
RETENTION
Not much urine is passed. Contact your doctor now.
NMS
Neuroleptic Malignant Syndrome includes a
high body temperature, muscle stiffness and
being unable to move.
It usually occurs within a few weeks of a dose change. Contact your doctor
immediately. Keep cool, with fans or cool water.
What about alcohol?
It is officially recommended that people taking zuclopenthixol should not drink alcohol. This is because both zuclopenthixol and alcohol
can cause drowsiness. If the two are taken at the same time, severe drowsiness can result. This can lead to falls or accidents. As well
as this, drinking alcohol often makes psychosis worse. Excessive drinking is especially likely to do this. Once people are used to taking
medication, they can sometimes drink alcohol in small amounts without any harm. Avoid alcohol altogether for the first one or two
months. After this, if you want a drink, try a glass of your normal drink and see how you feel. If this doesn’t make you feel drowsy, then
it is probably OK to drink small amounts. It pays to be very cautious because alcohol affects people in different ways, especially when
they are taking medication. Don't stop taking your medication because you fancy a drink. Discuss any concerns you may have with
your doctor, pharmacist or nurse. If you do drink alcohol, drink only small amounts. Never drink any alcohol and drive.
Remember, leaflets like this can only describe some of the effects of medication. You may find other
books or leaflets also useful. If you have access to the internet you may find a lot of information
there as well, but be careful, as internet based information is not always accurate.
2001 United Kingdom Psychiatric Pharmacy Group www.ukppg.org.uk
This leaflet is to help you understand about your medicine. It is not an official manufacturer's Patient Information Leaflet. For more
information call the UKPPG National Telephone Helpline, 11am to 5pm, Monday to Friday on 020 7919 2999 or visit
www.nmhct.nhs.uk/pharmacy
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