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Step 1: Track your symptoms

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1
Eye bulging
Pulled back eyelids
Swollen, puffy eyelids
Drooping or twitching eyelids
Dry, gritty eyes
Redness in/around the eye
Watery, teary eyes
Eye pain
Light sensitivity
Eyes pointing in different
directions
Blurry vision
Double vision
Color vision loss
Vision loss
Step 1: Track your symptoms
Bring this guide to your next appointment so you and your doctor can discuss
your symptoms and develop the best treatment plan for you.
Changes to your eyes
Over the past month, how often have you experienced the following
Thyroid Eye Disease (TED) symptoms? (Check the boxes that apply.)
All the time
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Sometimes
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Never
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2
Walking outdoors
Reading
Driving
Watching TV
Cooking
Working
Walking up or down stairs
Step 2: Share how TED is impacting
your daily life
Daily life
Thyroid Eye Disease (TED) can have an impact on your ability to do daily tasks.
Over the past month, has TED made it harder to do any of these daily tasks?
(Check the boxes that apply.)
Yes
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No
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Not sure
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Are there any other activities or hobbies that you wanted to do but could not
because of TED? (Use the space below to write your answer.)
3
Depressive feelings
Anxiety
Feeling like you are being
watched or judged
Hiding your appearance in public
Having a hard time making
normal facial expressions
Having difficulty holding
face-to-face conversations
Feeling disconnected from
friends, family, and hobbies
Wellbeing
The emotional effects of Thyroid Eye Disease (TED) should not be ignored.
It’s important that you talk with your doctor about how TED affects all aspects
of your life. Over the past month, have you noticed any of the following?
(Check the boxes that apply.)
Yes
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No
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Not sure
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Are there other ways that TED has changed how you feel about yourself?
(Use the space below to write your answer.)
4
Please see Important Safety Information on pages 6-7 and
Full Prescribing Information at TEPEZZA.com.
Step 3: Ask your doctor
about TEPEZZA
What are the possible side effects of TEPEZZA?
How might TEPEZZA reduce some of my TED symptoms?
How is TEPEZZA different from other treatments?
If you feel TEPEZZA is right for me, how will I receive it?
Could TEPEZZA be right for me?
5
Please see Important Safety Information on pages 6-7 and
Full Prescribing Information at TEPEZZA.com.
More questions for your doctor
Use the space below to write in any other questions you may have.
Use selfies to help you track changes
Taking selfies is a great way to keep track of how symptoms and
appearance are changing over time. Try to zoom in on your eyes when
you take your selfie, and make sure that your face is well lit.
If you have questions about Thyroid Eye Disease (TED), TEPEZZA, or this guide,
call a Nurse Advocate at 1-844-483-7399, Monday-Friday 8 AM-8 PM, ET.
Nurse Advocates do not provide individual patient care or medical advice.
6
Use and Important Safety Information
USE
TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about TEPEZZA?
Infusion reactions can happen during or within 24 hours after your infusion
of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or
nurse will slow or stop your infusion and treat your reaction. If you have a
severe infusion reaction, your doctor may stop your treatment completely.
Tell your doctor or nurse right away if you have any of these symptoms
during or after your treatment with TEPEZZA:
• High blood pressure
• Fast heartbeat
• Redness of the face/Feeling hot
If you have inflammatory bowel disease (IBD), such as Crohn’s disease or
ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms
of worsening IBD may include: an increased number of loose stools with
stomach pain or cramps, and blood in your stools. After each TEPEZZA
infusion, tell your doctor right away if you have worsening IBD symptoms.
TEPEZZA may cause an increase in your blood sugar. Before starting
treatment with TEPEZZA, tell your doctor if you are currently being treated
for diabetes, know your blood sugar is high, or have been diagnosed with
diabetes. It is important for you to take your treatments and follow an
appropriate diet for glucose control as prescribed by your doctor.
Before receiving TEPEZZA, tell your doctor if you:
• Have inflammatory bowel disease (Crohn’s disease or ulcerative colitis).
• Are currently being treated for diabetes, have been diagnosed with
diabetes, or know your blood sugar is high.
• Difficulty breathing
• Headache
• Muscle pain
7
• Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn
baby. Tell your doctor if you become pregnant or suspect you are pregnant
during treatment with TEPEZZA.
o
Women who are able to become pregnant should use an effective form
of birth control (contraception) prior to starting treatment, during
treatment and for at least 6 months after the final dose of TEPEZZA.
• Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes
into your breast milk. Talk to your doctor about the best ways to feed your
baby during treatment with TEPEZZA.
• Tell your doctor about all the medicines you take, including prescription
and over the counter medicines, vitamins, dietary and herbal
supplements. Know the medicines you take. Keep a list of them to show
your doctor and pharmacist when you get a new medicine.
What are the possible side effects of TEPEZZA?
The most common side effects of TEPEZZA include muscle cramps or spasms,
nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems,
taste changes, headache, and dry skin.
This is not a complete list of all possible side effects. Tell your doctor or
treatment team if you have any side effect that bothers you or that does not
go away.
Please visit TEPEZZA.com for more information.
You are encouraged to report negative side effects of prescription drugs
to the FDA. Visit www.fda.gov/safety/medwatch, or call the FDA at
1-800-FDA-1088.
Important Safety Information (continued)
TEPEZZA and the HORIZON logo are trademarks owned by or licensed to Horizon.
© 2020 Horizon Therapeutics plc P-TEP-00366 06/20
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Step 1: Track your symptoms

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Completed 26 March 2021

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