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LockandKe
Model
Beforeansweringthequestionsbelow,createyourownmodelofametabolicreactioninvolvingan
enzymeandtwosubstrates.Choosematerialsfromyourenvironment(schoolorhome)thatcanbe
molded,cut,orotherwisealteredtocreateamodelofanenzymedoingitswork.Inyourmodel,besure
you
todemonstratethespecialized“lockandkey”fitthattheenzymehaswiththesubstrates.Labelthe
partsofyoumodel—substrates,enzyme,enzyme/substratecomplex,andproduct(s).Whenyouare
finishedconstructingyourmodel,takeaphotographthatyoucansubmittoyourteacheralongwiththis
worksheet.Thenanswerthe
questionsbelowinyourownwords.
1.Whatistherelationshipbetweenanenzymeandthesubstratesitcanbind?
2.Whatismeantbythelockandkeymodel?Explaintherelationshipbetweenenzymesandsubstrates
bydescribingthemodelthatyoucreated.
3.Think
aboutwhatthelockandkeymodelmeansformetabolisminacell.Whathappensifacell
cannotproducetheenzymenecessaryforaspecificmetabolicreaction?